节镍型奥氏体不锈钢的组织性能对比

针对200系J5A、J5两种牌号节镍型奥氏体不锈钢冷轧压延性能的差异,对比分析J5A、J5钢成分设计、组织、力学性能和马氏体含量,研究冷加工性能差异产生的机理。结果表明:由于J5A钢成分设计不合理,镍当量较低,奥氏体稳定性较差,马氏体转变点M_d(30/50)高,在轧制过程中产生大量冷加工变形诱变马氏体,加工硬化程度严重,压延性能差。     

中国智能机械制造评价及发展研究

以中国规模以上工业企业数据库为基础，结合在智能制造主要区域调研的结果，筛选出15145家智能制造企业，经同行评议后，生成322家候选企业名单；再由资深产业专家从“开发式创新”和“探索式创新”两个方面去考察候选企业的能力，得到中国智能制造百强排行榜；随后根据行业分类，得到智能机械制造企业排行榜。在概述了智能机械制造上榜企业的基本情况后，着重分析了前20强企业，并提出了中国智能机械制造发展路径和未来的发展趋势。     

封隔器胶筒高温高压密封性能检测试验研究

设计研制一种封隔器胶筒密封性能试验装置。该装置可模拟油井下350℃高温、20 MPa高压恶劣工况,能够模拟封隔器胶筒坐封过程,能够对封隔器胶筒的密封性能进行检测。借助试验装置对不同形式的胶筒进行环空密闭试验,测试了不同形式封隔器胶筒在不同介质下环空腔内压力变化规律,得到了试验后胶筒的形变状态、腐蚀破损情况,检验了各形式胶筒在高温高压工况下的密封性能,为封隔器胶筒的设计和改进提供可靠的试验依据。     

耐低温露点腐蚀非金属空气预热器的性能及应用

从解决炼油厂加热炉空气预热器的低温露点腐蚀问题出发,分析讨论了耐腐蚀非金属材料(搪瓷、玻璃、氟塑料、石墨及陶瓷等)空气预热器的材料性能、结构形式、传热性能和工业应用效果.分析表明:石墨和陶瓷空气预热器具有优异的耐腐蚀性能和稳定的结构强度,可以在烟气酸露点以下温度安全使用.     

Thermal-Disrupting Interface Mitigates Intercellular Cohesion Loss for Accurate Topical Antibacterial Therapy

Bacterial infections remain a leading threat to global health because of the misuse of antibiotics and the rise in drug-resistant pathogens. Although several strategies such as photothermal therapy and magneto-thermal therapy can suppress bacterial infections, excessive heat often damages host cells and lengthens the healing time. Here, a localized thermal managing strategy, thermal-disrupting interface induced mitigation (TRIM), is reported, to minimize intercellular cohesion loss for accurate antibacterial therapy. The TRIM dressing film is composed of alternative microscale arrangement of heat-responsive hydrogel regions and mechanical support regions, which enables the surface microtopography to have a significant effect on disrupting bacterial colonization upon infrared irradiation. The regulation of the interfacial contact to the attached skin confines the produced heat and minimizes the risk of skin damage during thermoablation. Quantitative mechanobiology studies demonstrate the TRIM dressing film with a critical dimension for surface features plays a critical role in maintaining intercellular cohesion of the epidermis during photothermal therapy. Finally, endowing wound dressing with the TRIM effect via in vivo studies in S. aureus infected mice demonstrates a promising strategy for mitigating the side effects of photothermal therapy against a wide spectrum of bacterial infections, promoting future biointerface design for antibacterial therapy.     

Dynamic Stabilization of DNA Assembly by Using Pyrrole-Imidazole Polyamide

We used N-methylpyrrole (Py)-N-methylimidazole-(Im) polyamide as an exogenous agent to modulate the formation of DNA assemblies at specific double-stranded sequences. The concept was demonstrated on the hybridization chain reaction that forms linear DNA. Through a series of melting curve analyses, we demonstrated that the binding of Py−Im polyamide positively influenced both the HCR initiation and elongation steps. In particular, Py−Im polyamide was found to drastically stabilize the DNA duplex such that its thermal stability approached that of an equivalent hairpin structure. Also, the polyamide served as an anchor between hairpin pairs in the HCR assembly, thus improving the originally weak interstrand stability. We hope that these proof-of-concept results can inspire future use of Py−Im polyamide as a molecular tool to modulate the formation of DNA assemblies.     

工程水压爆破在煤层爆破中的应用

通过黑岱沟露天煤矿的工程试验总结了工程水压爆破技术(水土复合填塞炮孔)的原理及在露天煤矿爆破施工中的应用效果。在露天煤矿爆破施工中采用工程水压爆破技术,可以提高煤层爆破的大块率,降低单位立方岩石耗药量,降低爆破气体的温度,同时可以降低煤层爆破失火率、粉尘排放量,有效地控制爆破飞石。